PROBIOTIC
The Food and Agriculture Organization/World Health Organization defines “Probiotic” as living organisms, that when administered in proper amounts, can be beneficial to the host . In the past two decades Probiotic bacteria have increased in popularity in the dietary supplemental field. This is supported by numerous studies that show the benefits of probiotics in the immune system as well as other areas.
Probiotic bacteria is mostly gram positive bacteria such as lactobacillus and bifidobacterium genera. Numerous studies show the benefits of probiotic bacteria in gastrointestinal balance and immunity health.
Schematic representation of the interaction between host intestinal immune cells and probiotics. Probiotics play a role in host innate and adaptive immune responses by modulating immune cells.
How probiotic helps with gastrointestinal and immunity health ?
Probiotic helps B cells produce IgAs which acts as an anti inflammatory antibody that boosts the mechanisms of the mucosal/systemic immunity system. Probiotics have also been found to be beneficial for the elderly. Animal studies show that probiotics have antitumor as well as anti-allergic properties by reducing the IgE level in the body.
What is the safe way to take probiotics?
Probiotics are measured in CFUs ( Colony Forming Units ). The daily recommended dose of probiotics in adults is 1-10 billion CFUs.
Reference
Mazziotta C, Tognon M, Martini F, Torreggiani E, Rotondo JC. Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health. Cells. 2023 Jan 2;12(1):184. doi: 10.3390/cells12010184. PMID: 36611977; PMCID: PMC9818925.
https://www.mdpi.com/2073-4409/12/1/184
The Office of Dietary Supplements (ODS), part of the National Institutes of Health (NIH)
https://ods.od.nih.gov/factsheets/Probiotics-HealthProfessional/